Figure 1. Magnetic hyperthermia therapy. (A) In vivo magnetic hyperthermia therapy: magnetic nanoparticles are injected locally in glioblastoma tumor and submitted to alternating magnetic field; (B) On-a-chip magnetic hyperthermia process: dispersed magnetic nanoparticles in aqueous medium are injectable in central cavity of the chip, becoming in contact with 3D cell culture of tumor cells and posteriorly submitted to alternating magnetic field. The red drawing in frame shows brown solution of magnetic nanoparticles filling the chip cavity; (C) Microfluidic device (chip).