Table 1. Major histologic lesions in animals infected with peste des petits ruminants and concurrent diseases, Mongolia, 2016–2017*.
Lesion or disease |
Animal ID nos. |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Mongolian saiga |
|
Goitered gazelle |
|
Ibex |
||||||||
4 |
5, 8† |
9 |
10 |
11 |
17 |
13, 15† |
18 |
25 |
20 |
|||
PPRV-specific lesions | ||||||||||||
Oro/pharyngeal mucosa: erosion, epithelial necrosis, multifocal, acute (stomatitis, necrotizing) | +++, S+ | +++, S+ | +, S+ | – | – | +++, S+, I+ (IN) | – | +, S+ | NE | NE | ||
Liver: degeneration and necrosis, hepatocytes, multifocal, random, acute (hepatitis, necrotizing) | NE | NE | ++, S+, I+++ (IC and IN) | ++ | + | ++ | NE | ++, S+, I+ (IN) | ++, S+, I+ (IN>IC) | NE | ||
Liver: degeneration and necrosis, biliary epithelium, bile ductules, multifocal, acute | NE | NE | +, I++ (IC>IN) | – | – | – | NE | + | ++ I+ (IN>IC) | NE | ||
Liver: cholestasis, canalicular, acute | NE | NE | + | + | – | – | NE | – | – | NE | ||
Liver: hyperplasia, bile ductules, chronic | NE | NE | + | ++ | – | – | NE | – | – | NE | ||
Lung: degeneration and necrosis, bronchiolar epithelium, multifocal, acute | NE | NE | +, S+, I+(IN and IC) | – | – | – | NE | – | ++ S+ I++ (IN and IC) | NE | ||
Intestine: necrosis, crypt
epithelium, multifocal, acute |
NE |
NE |
+, I+ (IC>IN) |
–/PMA |
– |
–/PMA |
NE |
|
–/PMA |
–/PMA |
|
NE |
Concurrent diseases | NA | NA | NA | NA | Proliferative stomatitis, parapoxvirus suspected | NA | NA | NA | Bacterial sepsis with bacteremia | NA |
*I, presence of viral inclusion bodies; IC, intracytoplasmic inclusion; ID, identification; IN, intranuclear inclusion; NA, not applicable; NE, not examined; PMA, assessment hindered by postmortem autolysis; S, presence of syncytia; +, mildly severe; ++, moderately severe; +++, severe; –, lesion not found. †Tissue samples pooled.