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. Author manuscript; available in PMC: 2019 Dec 20.
Published in final edited form as: Methods Mol Biol. 2013;978:73–92. doi: 10.1007/978-1-62703-293-3_6

Fig. 1.

Fig. 1.

Overview of methods for the in vitro selection or screening of proteins discussed in this review. (A) The top row shows different strategies to establish the crucial linkage between gene and protein. (B) The bottom row illustrates the introduction of substrate into the selection scheme to enable the evolution of enzymes.