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. 2019 Dec 20;5(12):eaay2118. doi: 10.1126/sciadv.aay2118

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Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 2 — (A) Complete map of changes in mitochondrial transcript abundance determined by RNA-Seq coverage from control (L/L) and knockout (L/L, cre) mice on heavy (outer track) and light (inner track) strands. Increases are shown in red, and decreases are shown in blue (log₂[RPM_KO/RPM_WT]; scale, −1.0 to 2.0). The mitochondrial genome is displayed in the central track, with the nucleotide position in base pairs displayed across the exterior; rRNAs are displayed in orange, mRNAs are in green, tRNAs are in blue, and the noncoding region (NCR) is in gray. (B) Genome browser view of the mean RNA-Seq coverage (log₂[RPM_KO/RPM_WT] of Co1 and Atp8/6 mRNAs (scale, −0.6 to 2.1).