Fig. 3.

Confirmation of reduced cardiac disease inmdxmice at 90 days after systemic-intraosseous DEC (MB^wt/MB^mdxDEC and MB^wt/MSC^mdx) transplant confirmed by B-mode echocardiography. B-Mode image of parasternal long axis view of left ventricle of mdx vehicle control (left column) and mdx mice systemically injected with MB^wt/MB^mdx DEC (middle column) and MB^wt/MSC^mdx (right column) (Vevo 2100, VisualSonics). Day 0, 30, and 90 B-mode echo images of mdx vehicle controls demonstrate a trend of posterior wall disorganization and thickening. Though a degree of disorganization and thickening still occurs in both MB^wt/MB^mdx and MB^wt/MSC^mdx DEC treated mice, this effect appears dampened compared to the vehicle controls across the same corresponding time points