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. 2019 Oct 15;15(6):827–841. doi: 10.1007/s12015-019-09916-0

Table 1.

Echocardiographic assessment of morphometric cardiac parameters at day 0 and in response to DEC therapy at 30 and 90 days after systemic DEC transplant in mdx mice

Experimental group/ Timepoint Morphometric Parameters
LVESD (mm) LVEDD (mm) LVESV (μl) LVEDV (μl)
Day 0
  Vehicle (n = 3) 1.75 ± 0.32 3.18 ± 0.36 9.46 ± 4.61 40.89 ± 11.65
  MBwt + MBmdx (n = 3) 1.76 ± 0.05 2.96 ± 0.03 10.83 ± 0.79 31.50 ± 1.41
  MBwt + MSCmdx (n = 3) 1.71 ± 0.17 2.65 ± 0.40 10.92 ± 0.99 31.51 ± 2.94
  MBwt/MBmdx (n = 4) 2.02 ± 0.57 3.25 ± 0.61 14.52 ± 10.5 44.35 ± 19.28
  MBwt/MSCmdx (n = 3) 0.78 ± 0.73 1.88 ± 1.06 2.51 ± 3.84 15.27 ± 18.09
Day 30
  Vehicle (n = 3) 1.01 ± 0.59 2.33 ± 0.14 3.68 ± 3.48 18.81 ± 2.86
  MBwt + MBmdx (n = 3) 1.71 ± 0.13 2.55 ± 0.15 9.31 ± 1.03 24.51 ± 0.22
  MBwt + MSCmdx (n = 3) 1.86 ± 0.14 2.77 ± 0.16 10.12 ± 1.12 26.64 ± 0.24
  MBwt/MBmdx(n = 4) 2.40 ± 0.49 3.28 ± 0.31†‡ 21.28 ± 11.43 44.01 ± 10.41
  MBwt/MSCmdx (n = 3) 1.48 ± 0.82 2.00 ± 0.93 9.14 ± 8.30 23.90 ± 19.21
Day 90
  Vehicle (n = 3) 2.49 ± 0.52 3.29 ± 0.60 23.82 ± 11.48 46.10 ± 19.42
  MBwt + MBmdx (n = 3) 1.63 ± 0.30 2.60 ± 0.31 9.09 ± 4.49 28.75 ± 8.72
  MBwt + MSCmdx (n = 3) 1.79 ± 0.33 2.86 ± 0.34 9.99 ± 4.93 31.59 ± 9.58
  MBwt/MBmdx (n = 4) 2.03 ± 0.26 2.91 ± 0.29 13.62 ± 4.42 32.85 ± 8.20
  MBwt/MSCmdx (n = 3) 1.76 ± 0.05 2.89 ± 0.32 9.16 ± 0.66 32.61 ± 8.62

LVESD = left ventricular end systolic diameter, LVEDD = left ventricular end diastolic diameter, LVESV = left ventricular end systolic volume; LVEDV = left ventricular end diastolic volume; All values expressed as mean ± standard error; Significant increase (p < 0.05) compared to vehicle group; Significant increase (p < 0.05) compared to corresponding non-fused cell group; †‡ Significant increase (p < 0.05) compared to vehicle and corresponding non-fused cell group