Table A2.
Differentially expressed metabolites
| ID | Peak | Similarity | rt | Count | Mass |
Mean Ba |
Mean Aa |
VIP | p‐Value | Q‐value | Fold change | LOG_Foldchange |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 258 | Glycine 2 | 900 | 10.9412,0 | 22 | 174 | 0.000636555 | 0.000905682 | 1.681654595 | .021360277 | .470350794 | 0.702845776 | −0.508719938 |
| 530 | Myristic acid | 864 | 17.4935,0 | 22 | 117 | 0.000471343 | 0.000733843 | 2.026548698 | .039435112 | .495496165 | 0.642293626 | −0.638695115 |
| 580 | Methyl heptadecanoate | 838 | 19.2904,0 | 22 | 74 | 0.00061175 | 0.001137859 | 2.602664342 | .007154043 | .392233078 | 0.537632544 | −0.895307626 |
| 230 | Ethanolamine | 773 | 10.3913,0 | 22 | 174 | 0.000817073 | 0.002089325 | 1.882824161 | .008936497 | .412793867 | 0.391070269 | −1.354500236 |
| 596 | Myo‐inositol | 725 | 19.7907,0 | 22 | 217 | 5.2432E−05 | 0.000127505 | 2.213988037 | .032643332 | .488588572 | 0.411215558 | −1.282033246 |
| 537 | Fructose 2 | 677 | 17.6171,0 | 16 | 73 | 0.001503234 | 0.000264768 | 2.298420367 | .000201223 | .062032217 | 5.677560028 | 2.505271054 |
| 351 | Beta‐Alanine 2 | 641 | 12.565,0 | 19 | 248 | 2.14344E−05 | 4.88161E−05 | 1.005140441 | .044227856 | .499171803 | 0.439084406 | −1.187429797 |
| 571 | Gluconic acid 1 | 634 | 18.8501,0 | 22 | 73 | 0.001331955 | 0.000486406 | 2.181312099 | .018254163 | .46245845 | 2.738360012 | 1.45331213 |
| 126 | 3‐Hydroxypropionic acid 1 | 628 | 8.64861,0 | 15 | 147 | 0.000227447 | 3.86729E−05 | 1.89809182 | .003786769 | .320961262 | 5.881290599 | 2.556132777 |
| 564 | Ascorbate | 617 | 18.4939,0 | 22 | 117 | 0.000141637 | 0.000236679 | 1.729992969 | .029429218 | .484560963 | 0.598435492 | −0.740732353 |
| 555 | Sedoheptulose | 575 | 18.229,0 | 22 | 204 | 0.000143338 | 8.29165E−05 | 1.443433138 | .019096923 | .46482548 | 1.728704982 | 0.789691682 |
| 263 | Unknown | 553 | 11.028,0 | 22 | 174 | 0.000279223 | 0.000424518 | 1.915006827 | .011902268 | .435631776 | 0.657739563 | −0.604411643 |
| 88 | Unknown | 473 | 7.87172,0 | 15 | 154 | 5.92006E−05 | 2.74291E−05 | 2.172911772 | .019095927 | .464822792 | 2.158313081 | 1.109904155 |
| 774 | Dioctyl phthalate | 464 | 23.6597,0 | 22 | 149 | 0.000116688 | 0.000161225 | 1.681681562 | .023504702 | .474694377 | 0.723760618 | −0.466415487 |
| 306 | 2,3‐Dimethylsuccinic acid | 413 | 11.7677,0 | 22 | 221 | 0.000942685 | 0.000548862 | 1.104732534 | .028256141 | .482882576 | 1.717528774 | 0.780334269 |
| 341 | N‐Ethylglycine 1 | 407 | 12.322,0 | 20 | 142 | 0.000365908 | 0.001677752 | 2.011080769 | .00030861 | .072366056 | 0.218094053 | −2.196977662 |
| 815 | Androstanediol | 394 | 24.7242,0 | 22 | 215 | 0.000645328 | 0.0009989 | 2.361081193 | .013021745 | .44196591 | 0.646039227 | −0.630306329 |
| 487 | Unknown | 385 | 16.1412,0 | 4 | 73 | 9.78762E−05 | 1.33238E−09 | 1.927482839 | .046504973 | .501498802 | 73,459.62957 | 16.164664 |
| 390 | 4‐Acetamidobutyric acid 2 | 381 | 13.516,0 | 21 | 174 | 0.000197373 | 0.000376937 | 1.067381356 | .021187565 | .469966567 | 0.523624016 | −0.933396828 |
| 84 | Analyte 101 | 338 | 7.82067,0 | 15 | 147 | 6.42091E−05 | 1.96573E−05 | 2.191516203 | .025125818 | .477710913 | 3.266430242 | 1.70771483 |
| 652 | Unknown | 338 | 21.1104,0 | 11 | 183 | 0.000352283 | 1.33238E−09 | 2.158139288 | .041964778 | .497534124 | 264,401.0212 | 18.01236822 |
| 459 | Unknown | 332 | 15.2644,0 | 4 | 73 | 1.28223E−09 | 0.000450593 | 1.798650896 | .036228371 | .492533753 | 2.84565E−06 | −18.42280931 |
| 378 | Unknown | 328 | 13.2206,0 | 22 | 174 | 0.00022994 | 0.0003076 | 1.986934543 | .005907729 | .372603568 | 0.747529218 | −0.419798125 |
| 192 | Unknown | 326 | 9.71867,0 | 10 | 103 | 6.4026E−05 | 6.36615E−06 | 1.750377931 | .028741275 | .483591877 | 10.05726382 | 3.330165953 |
| 757 | Salicin | 322 | 23.2598,0 | 22 | 268 | 0.001969318 | 0.002926527 | 2.097665134 | .037881974 | .494119578 | 0.67291969 | −0.571493758 |
| 755 | Neohesperidin | 316 | 23.2301,0 | 22 | 259 | 0.002558287 | 0.003988477 | 2.278077859 | .015242434 | .45214943 | 0.641419517 | −0.640659842 |
| 651 | Unknown | 311 | 21.0898,0 | 11 | 127 | 0.000291231 | 1.33238E−09 | 2.273471926 | .021554222 | .470775646 | 218,579.3535 | 17.73779761 |
| 814 | dihydrotestosterone | 307 | 24.7072,0 | 22 | 254 | 0.000682601 | 0.001060085 | 2.368585174 | .015266066 | .45224402 | 0.64391169 | −0.635065252 |
| 157 | Unknown | 304 | 9.12182,0 | 11 | 267 | 0.000379069 | 4.13821E−05 | 2.697230347 | 9.50082E−06 | .006683556 | 9.160218651 | 3.195382035 |
| 690 | Unknown | 302 | 21.7667,0 | 22 | 74 | 0.001128332 | 0.001688802 | 2.30097913 | .009361508 | .416774798 | 0.668126012 | −0.581807866 |
| 752 | Analyte 867 | 300 | 23.1975,0 | 22 | 113 | 0.002689158 | 0.004064865 | 2.125973172 | .042392132 | .497855921 | 0.661561578 | −0.596052646 |
| 454 | Unknown | 299 | 15.2144,0 | 4 | 155 | 1.28223E−09 | 3.31542E−05 | 1.796567609 | .036471165 | .492774945 | 3.86747E−05 | −14.65825047 |
| 751 | Analyte 866 | 290 | 23.1883,0 | 22 | 226 | 0.014606521 | 0.021855725 | 2.109873509 | .044279473 | .499207322 | 0.668315535 | −0.581398685 |
| 165 | Unknown | 289 | 9.20858,0 | 20 | 174 | 0.000165965 | 0.000280953 | 1.587651675 | .026109306 | .479456879 | 0.590723043 | −0.759446204 |
| 760 | Analyte 875 | 287 | 23.3164,0 | 22 | 173 | 0.003045102 | 0.004570994 | 2.342115269 | .014707448 | .449938128 | 0.666179422 | −0.586017305 |
| 273 | 4‐Acetylbutyric acid 2 | 285 | 11.1765,0 | 21 | 174 | 4.44156E−05 | 9.38684E−05 | 1.309081961 | .005491246 | .364658429 | 0.473168653 | −1.079573597 |
| 711 | Unknown | 285 | 22.4259,0 | 20 | 226 | 0.000201512 | 0.000429821 | 2.096817887 | .02126821 | .470146675 | 0.468826647 | −1.092873522 |
| 770 | Analyte 885 | 276 | 23.5711,0 | 16 | 145 | 9.06817E−05 | 0.00019568 | 1.310305407 | .042568261 | .497986784 | 0.463418625 | −1.109612068 |
| 483 | Glutamine 2 | 269 | 16.024,0 | 12 | 154 | 7.28123E−05 | 0.001285245 | 2.016098221 | .028042727 | .482563457 | 0.056652467 | −4.141717403 |
| 667 | Unknown | 258 | 21.3307,0 | 21 | 98 | 0.000197059 | 0.000289329 | 1.70059336 | .008320611 | .406463982 | 0.681091293 | −0.554079906 |
| 694 | Glucose−6‐phosphate 2 | 258 | 21.8499,0 | 12 | 86 | 0.000205605 | 3.82541E−05 | 1.684651431 | .04010425 | .496058575 | 5.374703563 | 2.426185186 |
| 87 | Analyte 104 | 252 | 7.87963,0 | 18 | 89 | 3.6662E−05 | 9.50563E−05 | 1.643073189 | .03634495 | .492649936 | 0.385687373 | −1.374496179 |
| 168 | Unknown | 247 | 9.26721,0 | 17 | 281 | 6.1893E−05 | 2.01719E−05 | 1.45803412 | .005665154 | .368076045 | 3.068280644 | 1.617430447 |
| 607 | Analyte 701 | 240 | 20.0942,0 | 6 | 87 | 4.73497E−05 | 0.000577686 | 1.693128043 | .042242217 | .497743729 | 0.081964356 | −3.608859529 |
| 281 | Allylmalonic acid | 234 | 11.3282,0 | 20 | 341 | 0.000138678 | 6.8898E−05 | 1.388553557 | .012405111 | .438595571 | 2.012805865 | 1.009208031 |
| 479 | Methoxamedrine 2 | 224 | 15.9526,0 | 6 | 166 | 5.29336E−05 | 0.00033931 | 1.965510146 | .035962702 | .492266383 | 0.156003567 | −2.680349077 |
| 709 | Analyte 819 | 208 | 22.3485,0 | 5 | 152 | 1.28223E−09 | 3.20059E−05 | 2.175696958 | .019925125 | .466977373 | 4.00623E−05 | −14.60739434 |
| 282 | Analyte 319 | 206 | 11.357,0 | 22 | 227 | 0.000111597 | 0.00020074 | 1.481083252 | .049254692 | .504321124 | 0.555931028 | −0.847022189 |
| 524 | Analyte 607 | 200 | 17.2762,0 | 22 | 74 | 0.000424919 | 0.000888424 | 2.139910283 | .012643434 | .439930975 | 0.478284016 | −1.064060517 |
| 754 | Biotin | 196 | 23.2218,0 | 22 | 201 | 0.000838393 | 0.001251854 | 2.182683791 | .030664975 | .486201342 | 0.669720659 | −0.578368623 |
| 753 | Analyte 868 | 161 | 23.2078,0 | 18 | 212 | 0.000712289 | 0.001480437 | 1.222977586 | .012945675 | .4415648 | 0.481134531 | −1.05548775 |
| 7 | Analyte 9 | 0 | 6.36885,0 | 8 | 159 | 0.000253871 | 1.33238E−09 | 1.842253232 | .03915136 | .495252265 | 190,539.333 | 17.53972932 |
| 8 | Analyte 10 | 0 | 6.39045,0 | 22 | 102 | 0.014832721 | 0.008723585 | 2.520788492 | .012259819 | .437760121 | 1.700301099 | 0.76579025 |
| 47 | Analyte 55 | 0 | 7.018,0 | 15 | 117 | 6.82734E−05 | 0.000187564 | 2.004841093 | .003449839 | .309299434 | 0.363999623 | −1.457991137 |
| 769 | Analyte 884 | 0 | 23.5743,0 | 10 | 110 | 0.000132283 | 1.33238E−09 | 2.762715307 | .000591452 | .10401739 | 99,282.83028 | 16.59925662 |
a
A and B represent the P. aeruginosa in the absence and presence of 4% glucose, respectively.