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. 2019 Sep 27;8(12):e937. doi: 10.1002/mbo3.937

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© 2019 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Change in gene expression in biofilms under the effects of CUR. The mRNA levels of genes in different virulence systems of Streptococcus mutans and Candida albicans are shown in Figure 5. Different levels of gene expression were standardized to 16 sRNA levels. (a) Relative RNA expression of gtfs in S. mutans, (b) relative RNA expression of two‐component signal transduction system in S. mutans, and (c) relative RNA expression of als in C. albicans. The asterisks (*) indicated significant differences (*p < .05; **p < .01; ***p < .001)