Table 1.
Enriched KEGG pathways in differentially expressed genes.
| Pathway | No. of genes | FDR |
|---|---|---|
| TNF signaling pathway | 18/110 | 2.13 × 10−8 |
| Rheumatoid arthritis | 11/91 | 8.02 × 10−4 |
| Biosynthesis of amino acids | 10/75 | 8.02 × 10−4 |
| AGE-RAGE signaling pathway in diabetic complications | 11/100 | 1.41 × 10−3 |
| MAPK signaling pathway | 19/295 | 3.70 × 10−3 |
| NF-kappa B signaling pathway | 10/100 | 4.69 × 10−3 |
| Transcriptional misregulation in cancer | 14/186 | 4.69 × 10−3 |
| Glycine, serine and threonine metabolism | 6/40 | 9.15 × 10−3 |
| IL-17 signaling pathway | 9/93 | 9.15 × 10−3 |
| PPAR signaling pathway | 8/76 | 9.84 × 10−3 |
| Fluid shear stress and atherosclerosis | 11/139 | 1.00 × 10−2 |
| HIF-1 signaling pathway | 9/100 | 1.17 × 10−2 |
| Cysteine and methionine metabolism | 6/49 | 1.67 × 10−2 |
| Insulin resistance | 9/108 | 1.67 × 10−2 |
| One carbon pool by folate | 4/20 | 1.67 × 10−2 |
| Ras signaling pathway | 14/232 | 1.90 × 10−2 |
| Rap1 signaling pathway | 13/208 | 1.92 × 10−2 |
| Kaposi sarcoma-associated herpesvirus infection | 12/186 | 2.10 × 10−2 |
| Amoebiasis | 8/95 | 2.26 × 10−2 |
| Ferroptosis | 5/40 | 2.75 × 10−2 |
No. of genes is reported as the number of genes in the pathway identified as differentially expressed in this data set versus the total number of genes in the pathway.