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. 2019 Dec 20;10:5822. doi: 10.1038/s41467-019-13786-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a A hexamer–pentamer–hexamer subassembly from the T = 3 particle shown in surface representation viewed from the exterior of the shell (upper) and from the side, highlighting the curvature (lower). NTDs and CTDs in the pentamer and those in the hexamer that interface with pentamers are coloured pink and cyan, respectively. NTDs and CTDs in the hexamer that interface with hexamers are coloured red and teal, respectively. b Cartoon representation of a hexamer from the T = 3 particle viewed down the icosahedral three-fold axis (colouring as in a). c, d NTD–CTD intra-hexamer interactions in the T = 3 hexamer. c A CA monomer, NTD (pink) and CTD (cyan) that interfaces with a neighbouring pentamer, and the adjacent NTD shown in red. d A CA monomer, NTD (red) and CTD (teal) that interfaces with a neighbouring hexamer, and the adjacent NTD is shown in pink. Residues making interactions are shown as sticks with hydrogen bonds shown as dashes, the prime (′) notation indicates the adjacent NTD and “mc” indicates a main-chain interaction. e NTD (pink/red) alignment of monomers in T = 3 hexamers showing the relative displacement of the CTD when the protomer interacts with either a neighbouring pentamer (cyan) or a neighbouring hexamer (teal). f Hexamer surface representation viewed perpendicular to the symmetry axis showing alternate CTDs displaced upwards (cyan, pentamer facing) and downwards (teal, hexamer facing). NTDs are coloured pink or red as in a.