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. 2019 Dec 20;9:19562. doi: 10.1038/s41598-019-55372-8

Table 6.

Average individual level health gain associated with five-years of double therapy with (3%) and without (0%) discounting to potentially facilitate more informed patient-clinician discussions around medication use (the values at 0% discount rate are in brackets)

Five-year cumulative absolute risk strata Quality-adjusted healthy months of life gained for the average cohort member from the offer of screening (intention-to-treat style of analysis) Quality-adjusted healthy months of life gained for those who respond to the screening offer and commence treatment*
Non-Māori Māori Non-Māori Māori
>20% 3.5 (5.2) 2.9 (4.1) 4.9 (7.3) 4.1 (5.8)
>15, ≤20% 2.4 (3.7) 2.1 (3.1) 3.4 (5.3) 3.0 (4.4)
>10, ≤15% 1.6 (2.6) 1.5 (2.2) 2.3 (3.6) 2.1 (3.1)
>5, ≤10% 0.8 (1.4) 0.9 (1.3) 1.2 (1.9) 1.2 (1.9)
>0, ≤5% 0.4 (0.7) 0.5 (0.7) 0.6 (1.0) 0.7 (1.0)

*Albeit with the reduction in adherence as in the base-case model of 22.5% over the five-year period of treatment.