Skip to main content
. Author manuscript; available in PMC: 2020 Dec 20.
Published in final edited form as: ACS Chem Biol. 2019 Oct 14;14(12):2595–2605. doi: 10.1021/acschembio.9b00482

Scheme 1.

Scheme 1

a Reagents and conditions: (i) R1-amine, TEA, DMSO, 80 °C, 18 hr, (ii) 4-aminophenols, 5-aminonaphthols, or 4-aminonaphthols, K2CO3, DMF, 155 °C, μW, 2 hr (iii) sulfonyl chloride, pyridine, DCM, RT, 18 hr (iv) TFA:DCM (1:1), RT, 2 hr