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. 2019 Nov 25;40(48):3889–3897. doi: 10.1093/eurheartj/ehz766

Table 1.

Cancer patients and death from cardiovascular disease between 1973 and 2012

No. of cancer patients Index-cancer deaths
CVD deaths
Heart disease deaths
No. % of cancer patients No. % of cancer patients No. % of all CVD deaths
All patients 3 234 256 1 228 328 38.0 365 689 11.3 279 060 76.3
Sex
 Male 1 662 864 651 517 39.2 200 610 12.1 157 349 78.4
 Female 1 571 392 576 811 36.7 165 079 10.5 121 711 73.7
Age at diagnosis
 0–19 years 43 263 10 156 23.5 278 0.6 232 83.5
 20–39 years 210 699 54 047 25.7 2845 1.4 2330 81.9
 40–59 years 932 545 326 003 35.0 41 356 4.4 32 622 78.9
 60–79 years 1 636 489 656 668 40.1 224 173 13.7 171 137 76.3
 80+ years 411 260 181 454 44.1 97 037 23.6 72 739 75.0
Year of diagnosis
 1973–82 564 129 294 723 52.2 109 144 19.3 82 941 76.0
  983–92 766 593 356 095 46.5 127 992 16.7 97 955 76.5
 1993–2002 911 959 338 260 37.1 97 014 10.6 73 780 76.1
 2003–2012 991 575 239 250 24.1 31 539 3.2 24 384 77.3
Race
 White 2 731 980 1 027 442 37.6 319 537 11.7 243 887 76.3
 Black 297 188 127 077 42.8 30 924 10.4 24 233 78.4
 Other 205 088 73 809 36.0 15 228 7.4 10 940 71.8
Marital status
 Single 399 184 141 885 35.5 28 848 7.2 22 463 77.9
 Married 1 894 691 699 628 36.9 200 897 10.6 153 711 76.5
 Separated 42 498 20 794 48.9 6740 15.9 5244 77.8
 Divorced 237 000 98 579 41.6 18 723 7.9 14 557 77.7
 Widowed 484 770 224 723 46.4 91 850 18.9 68 835 74.9
Stage at presentation
 Localized 1 059 957 169 107 16.0 148 767 14.0 111 465 74.9
 Regional 632 242 282 521 44.7 65 304 10.3 49 420 75.7
 Distant 528 923 389 794 73.7 25 220 4.8 20 052 79.5
Months since diagnosis
 2–11 months 3 234 256 519 279 16.1 45 592 1.4 35 925 78.8
 12–59 months 2 533 198 498 282 19.7 105 581 4.2 81 355 77.1
 60–179 months 1 493 858 176 561 11.8 148 842 10.0 112 673 75.7
 180–239 months 490 191 20 554 4.2 34 398 7.0 25 802 75.0
 240+ months 257 961 13 652 5.3 31 276 12.1 23 305 74.5
Top 10 cancer sites with the largest percent of CVD deaths
 Urinary bladder 143 846 34 079 23.7 27 907 19.4 21 618 77.5
 Larynx 32 564 12 019 36.9 5648 17.3 4393 77.8
 Prostate 509 128 89 722 17.6 84 534 16.6 65 355 77.3
 Corpus uteri 113 614 19 809 17.4 17 692 15.6 12 947 73.2
 Rectum 76 448 31 266 40.9 10 440 13.7 8057 77.2
 Breast 516 225 119 981 23.2 60 409 11.7 44 475 73.6
 Kidney and renal pelvis 77 882 27 165 34.9 8032 10.3 6198 77.2
 Non-Hodgkin lymphoma 125 567 50 504 40.2 10 989 8.8 8634 78.6
 Melanoma of the skin 121 290 17 904 14.8 9315 7.7 6968 74.8
 Lung and bronchus 377 956 289 842 76.7 22 463 5.9 18 076 80.5

In the SEER program, between 1973 and 2012, 3 234 256 cancer patients representing 28 different cancer sites were identified. Morality rates from index-cancer, cardiovascular diseases, and particularly heart disease are presented as a function of demographic variables.