Table 2.

Prevalence of Movement Disorders in Human Prionopathies

N	sCJD	vCJD	iCJD	gCJD	FFI	GSS	p-value
	N(%)	N(%)	N(%)	N(%)	N(%)	N(%)
	164	23	12	45	30	50
Gait ataxia	103 (62.8%)	21 (91.3%)	9 (75%)	30 (66.7%)	17 (56.7%)	37 (74%)	0.051
Limb ataxia	66 (40.2%)	9 (39.1%)	7 (58.3%)	24 (53.3%)	8 (26.7%)	10 (20%)	0.012
Myoclonus	96 (58.5%)	13 (56.5%)	8 (66.7%)	32 (71.1%)	20 (66.7%)	12 (24%)	<0.001
Tremor	8 (4.9%)	2 (8.7%)	1 (8.3%)	3 (6.7%)	4 (13.3%)	4 (8%)	0.47
Parkinsonism	12 (7.3%)	2 (8.7%)	1 (8.3%)	7 (15.6%)	4 (13.3%)	9 (18%)	0.24
Rigidity	72 (43.9%)	7 (30.4%)	3 (25%)	26 (57.8%)	7 (23.3%)	20 (40%)	0.037
Chorea	6 (3.7%)	7 (30.4%)	0 (0%)	0 (0%)	0 (0%)	2 (4%)	<0.001
Dystonia	15 (9.1%)	2 (8.7%)	0 (0%)	1 (2.2%)	0 (0%)	2 (4%)	0.28
Gaze palsy	18 (11%)	3 (13%)	1 (8.3%)	1 (2.2%)	0 (0%)	0 (0%)	0.011

Abbreviations: FFI, Fatal Familial Insomnia; gCJD, Genetic Creutzfeldt–Jakob Disease; GSS, Gerstmann–Sträussler–Scheinker Disease; iCJD, Iatrogenic Creutzfeldt–Jakob Disease; p-value, Fisher’s exact test; sCJD, Sporadic Creutzfeldt–Jakob Disease; vCJD, Variant Creutzfeldt–Jakob Disease.