Table 3.
Hemagglutination titers of PR8-infected MDCK cell supernatants in the presence of the pomegranate peel extract and its more effective fractions
| Extract/fractions | Concentration (μg/ml) | Log2 HA titer/50 μl supernatant | |||
|---|---|---|---|---|---|
| 24 hra | 48 hra | ||||
| Crude extract | |||||
| 50 | 0 | 0 | |||
| 25 | 0.67±1.15 | 4±3.46 | |||
| 12.5 | 1.67±1.15 | 6.33±0.58 | |||
| 6.25 | 2.67±1.15 | 6.67±1.15 | |||
| virus control | 5±1.4 | 7.33±.58 | |||
| n-butanol fraction | |||||
| 50 | 0 | 0 | |||
| 25 | 0 | 2.5±0.71 | |||
| 12.5 | 1.5±0.71 | 6 | |||
| 6.25 | 3.5±0.71 | 6.5±0.71 | |||
| virus control | 6 | 7.5±0.71 | |||
| Ethyl acetate fraction | |||||
| 25 | 0 | 1±1.73 | |||
| 12.5 | 0.33±0.58 | 4±1.43 | |||
| 6.25 | 1.67±1.53 | 6.33±0.58 | |||
| 3.12 | 2.67±0.58 | 6.67±1.15 | |||
| virus control | 4±1.73 | 7.33±0.58 | |||
| Oseltamivir (μmol)b | |||||
| 5 | 0 | 0 | |||
| 2.5 | 0 | 0.5±0.71 | |||
| 1.25 | 0 | 4 | |||
| virus control | 5±1.4 | 8 | |||
a:
Hours post-infection;
b:
Oseltamivir used as positive control.