Table 3.
Brain regions negatively correlated with the time on the Trail Making Test A (TMTA; significant at p < .05, FDR corrected) and positively correlated with raw scores on the Digit Symbol Substitution Test (DSST; significant at p < .001 uncorrected) for the DLB group
| Brain region | R/L | BA | k | x | y | z | T |
|---|---|---|---|---|---|---|---|
| TMTA (N = 87) | |||||||
| Cluster 1 | |||||||
| Caudate nucleus (head and body) | L | na | 1033/1646 | − 15 | 10.5 | 9 | 5.07* |
| Putamen | L | na | 121/1646 | − 18 | 15 | 3 | 3.71 |
| Globus pallidus | L | na | 18/1646 | − 13.5 | 4.5 | 3 | 3.6 |
| Thalamus (ventral anterior nucleus) | L | na | 21/1646 | − 10 | − 1.5 | 6 | 3.2 |
| Cluster 2 | |||||||
| Caudate nucleus (head and body) | R | na | 1000/1484 | 12 | 0 | 13.5 | 4.44 |
| Putamen | R | na | 114/1484 | 22.5 | 13.5 | 10.5 | 3.82 |
| Cluster 3 | |||||||
| Subthalamic nucleus | L/R | na | 230 | − 4.5 | − 13.5 | − 3 | 4.1 |
| DSST (N = 81) | |||||||
| Cerebellum | L | na | 268 | − 43.5 | − 70.5 | − 43.5 | 4.1 |
| Thalamus (ventral lateral nucleus) | L | na | 201 | − 15 | − 16.5 | 10.5 | 3.77 |
| Inferior frontal gyrus | R | 44/45 | 105 | 55.5 | 18 | 19.5 | 3.59 |
x, y, z MNI coordinates of the cluster peak; BA Brodmann area; k cluster extent; T t value for the cluster peak
*Cluster peak significant at p < .05 FWE corrected