Appendix Table B.1.
Comparison of analytic sample to group meeting all inclusion criteria with the exception of having follow-up data. Data were collected between June 2005 and February 2017.
| Analytic Sample |
Excluded - No Follow-up data |
P | |
|---|---|---|---|
| N | 12,242 | 3,622 | |
| African American or Black, N(%) | 1904 (15.6) | 742 (20.5) | <0.001 |
| Entry age in yrs, mean(SD) | 74.38 (7.94) | 73.78 (8.15) | <0.001 |
| Female Sex, N{%) | 7235 ( 59.1) | 2148 ( 59.3) | 0.841 |
| Died, N(%) | 1933 (15.8) | 397 (11.0) | <0.001 |
| Education Category | <0.001 | ||
| Under High School, N{%) | 446 (3.6) | 182 (5.0) | |
| High School, N(%} | 1915 (15.6) | 647 (17.9) | |
| Over High School, N(%) | 2314 (18.9) | 692 (19.1) | |
| Bachelor degree, N(%) | 2894 (23.6) | 801 (22.1) | |
| Masters degree, N(%) | 3270 (26.7) | 923 (25.5) | |
| Doctorate degree, N(%) | 1365 (11.2) | 356 (9.8) | |
| Unknown, N(%) | 38 (0.3) | 21 (0.6) | |
| Diabetes | <0.001 | ||
| Absent, N(%) | 10749 (87.8) | 3079 (85.0) | |
| Recent/active, N(%) | 1394 (11.4) | 499 (13.8) | |
| Remote/inactive, N(%) | 64 (0.5) | 33 (0.9) | |
| unknown, (N%) | 35 (0.3) | 11 (0.3) | |
| Hypertension | 0.006 | ||
| Absent, N(%) | 5743 (46.9) | 1608 (44.4) | |
| Recent/active, N(%) | 6139 (50.1) | 1878 (51.8) | |
| Remote/inactive, N(%) | 326 (2.7) | 119 (3.3) | |
| Unknown, (N%) | 34 (0.3) | 17 (0.5) | |
| Cardiac event/condition* | 0.058 | ||
| Absent, N(%) | 10568 (86.3) | 3070 (84.8) | |
| Recent/active, N(%) | 909 (7.4) | 299 (8.3) | |
| Unknown, (N%) | 765 (6.2) | 253 (7.0) | |
| Diagnosis at Baseline | |||
| Cognitively unimpaired | 8182 (66.8) | 2067 (57.1) | |
| Impaired-not-MCI | 0(0.0) | 0(0.0) | |
| MCI | 4060 (33.2) | 1555 (42.9) | |
| Dementia | 0 (0.0) | 0 (0.0) | |
| Referral Source | <0.001 | ||
| Self/relative/friend, N(%) | 4358 (35.6) | 1248 (34.5) | |
| Health professional, N(%) | 2757 (22.5) | 1181 (32.6) | |
| Other, N(%)† | 4688 (38.3) | 1106 (30.5) | |
| Unknown, N{%) | 439 (3.6) | 87 (2.4) | |
| Family History of dementia | <0.001 | ||
| No 1st degree relative, N(%) | 4522 (36.9) | 1501 (41.4) | |
| ≥ One 1st degree relative, N(%} | 6601 (53.9) | 1661 (45.9) | |
| unknown, (N%) | 1119 (9.1) | 460 (12.7) | |
| ≥ One follow-up visit, N(%) | 12.242 (100.0) | 0 (0) | <0.001 |
| Years of follow-up, mean (SD) | 4.55 (2.83) | 0(0) | <0.001 |
The designation of “recent/active” was given if the condition occurred within the year prior to the study visit or required active management in the case of chronic conditions and the report was consistent with information obtained during the subject and study partner interview. The label “remote/inactive” was indicated if the condition existed or occurred in the past or more than one year ago, but had resolved or no longer needed treatment or management. As implied, if a condition was reported by either the participant or the study partner or indicated from other records, it was designated as “absent” A label of “unknown” selected if there was insufficient data to determine the status of the condition.
Cardiac event/condition includes history of myocardial infarction (Ml), atrial fibrillation (AFib), and congestive heart failure {CHF). “Recent/active” selected if any of the three conditions were “recent/active’’; categorization “absent” if all three were “absent or “remote/inactive”, and “unknown” for combinations of “unknown”, “absent”, and “remote/inactive”.
The category of “Other” for Referral Source represents a mixture of categories, including Alzheimer’s Disease Center (ADC) solicitation, non-ADC study, population sample, or non-ADC media appeal.