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. 2019 Oct 30;2019:8413576. doi: 10.1155/2019/8413576

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Copyright © 2019 Wen-jing Dai et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Involvement of IL-10 in the inhibition of EA on spinal LTP. (a) The spinal LTP completely blocked by EA performed 30 min before the tetanic stimulation of the sciatic nerve (TSS) compared to sham-EA (P < 0.001, vs. sham-EA). (b) The IL-10 antibody (0.4 µg or 2 µg) recovered the spinal LTP suppressed by EA in a dose-dependent manner (P < 0.001, vs. IgG). (c) The spinal LTP was also recovered by IL-10 neutralizing antibody (2 µg) intrathecally injected 30 min after TSS (P < 0.05, vs. IgG).