Table 2.
The variation of proteins related to the calcium regulation.
| Receptors/proteins | Roles played by the proteins | EA vs. M | EAG vs. EA |
|---|---|---|---|
| A2b | Related to calcium regulation | ↑ | ↓ |
| Ryanodine 2 | Releasing Ca2+ from SR into the cytoplasm and related to the myocardial contraction | ↓ | ↑ |
| SERCA 2a | Calcium pump to uptake Ca2+ into SR and related to myocardial diastolic | ↑ | — |
| NCX1 | Removing Ca2+ from the cytoplasm by exchanging Na+ into the cells | — | — |
| P-PLB(S16)/PLB | Regulating the function of SERCA2a, related to uptake intracellular Ca2+ into SR | ↑ | ↓ |
| Troponin C/I | The binding degree of cardiac myocytes to calcium | ↓ | ↑ |
↑, upregulated; ↓, downregulated; —, unchanged.