Table 2.
Clinical characteristics | ACVR2B-AS1 expression | |||||||
---|---|---|---|---|---|---|---|---|
Variable | No. of patients | High | % | Low | % | χ 2 | p value | |
Age | <55 | 117 | 67 | (31.75) | 50 | (31.45) | 0 | 1.000 |
≥55 | 253 | 144 | (68.25) | 109 | (68.55) | |||
| ||||||||
Gender | Female | 121 | 71 | (33.65) | 50 | (31.25) | 0.1417 | 0.6557 |
Male | 250 | 140 | (66.35) | 110 | (68.75) | |||
| ||||||||
Histological type | Fibrolamellar | 3 | 1 | (0.47) | 2 | (1.25) | 1.2706 | 0.515 |
Hepatocellular | 361 | 207 | (98.1) | 154 | (96.25) | |||
Hepatocholangiocarcinoma | 7 | 3 | (1.42) | 4 | (2.5) | |||
| ||||||||
Histologic grade | G1 | 55 | 28 | (13.46) | 27 | (17.09) | 7.2563 | 0.054 |
G2 | 177 | 97 | (46.63) | 80 | (50.63) | |||
G3 | 122 | 72 | (34.62) | 50 | (31.65) | |||
G4 | 12 | 11 | (5.29) | 1 | (0.63) | |||
| ||||||||
Stage | I | 171 | 92 | (46.23) | 79 | (53.38) | 2.8209 | 0.458 |
II | 86 | 50 | (25.13) | 36 | (24.32) | |||
III | 85 | 53 | (26.63) | 32 | (21.62) | |||
IV | 5 | 4 | (2.01) | 1 | (0.68) | |||
| ||||||||
T Classification | T1 | 181 | 97 | (46.19) | 84 | (52.83) | 2.7575 | 0.647 |
T2 | 94 | 56 | (26.67) | 38 | (23.9) | |||
T3 | 80 | 47 | (22.38) | 33 | (20.75) | |||
T4 | 13 | 9 | (4.29) | 4 | (2.52) | |||
TX | 1 | 1 | (0.48) | 0 | (0) | |||
| ||||||||
N classification | N0 | 252 | 147 | (70) | 105 | (65.62) | 1.588 | 0.528 |
N1 | 4 | 3 | (1.43) | 1 | (0.62) | |||
NX | 114 | 60 | (28.57) | 54 | (33.75) | |||
| ||||||||
M Classification | M0 | 266 | 154 | (72.99) | 112 | (70) | 1.1272 | 0.597 |
M1 | 4 | 3 | (1.42) | 1 | (0.62) | |||
MX | 101 | 54 | (25.59) | 47 | (29.38) | |||
| ||||||||
Radiation therapy | No | 338 | 191 | (98.45) | 147 | (96.71) | 0.5046 | 0.307 |
Yes | 8 | 3 | (1.55) | 5 | (3.29) | |||
| ||||||||
Residual tumor | R0 | 324 | 183 | (88.83) | 141 | (89.24) | 0.8406 | 1.000 |
R1 | 17 | 10 | (4.85) | 7 | (4.43) | |||
R2 | 1 | 1 | (0.49) | 0 | (0) | |||
RX | 22 | 12 | (5.83) | 10 | (6.33) | |||
| ||||||||
Vital status | Deceased | 130 | 88 | (41.71) | 42 | (26.25) | 8.8834 | 0.003 |
Living | 241 | 123 | (58.29) | 118 | (73.75) |