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. 2019 Oct 30;2019:4602371. doi: 10.1155/2019/4602371

Table 2.

Correlation between the clinicopathologic variables and ACVR2B-AS1 expression.

Clinical characteristics ACVR2B-AS1 expression
Variable No. of patients High % Low % χ 2 p value
Age <55 117 67 (31.75) 50 (31.45) 0 1.000
≥55 253 144 (68.25) 109 (68.55)

Gender Female 121 71 (33.65) 50 (31.25) 0.1417 0.6557
Male 250 140 (66.35) 110 (68.75)

Histological type Fibrolamellar 3 1 (0.47) 2 (1.25) 1.2706 0.515
Hepatocellular 361 207 (98.1) 154 (96.25)
Hepatocholangiocarcinoma 7 3 (1.42) 4 (2.5)

Histologic grade G1 55 28 (13.46) 27 (17.09) 7.2563 0.054
G2 177 97 (46.63) 80 (50.63)
G3 122 72 (34.62) 50 (31.65)
G4 12 11 (5.29) 1 (0.63)

Stage I 171 92 (46.23) 79 (53.38) 2.8209 0.458
II 86 50 (25.13) 36 (24.32)
III 85 53 (26.63) 32 (21.62)
IV 5 4 (2.01) 1 (0.68)

T Classification T1 181 97 (46.19) 84 (52.83) 2.7575 0.647
T2 94 56 (26.67) 38 (23.9)
T3 80 47 (22.38) 33 (20.75)
T4 13 9 (4.29) 4 (2.52)
TX 1 1 (0.48) 0 (0)

N classification N0 252 147 (70) 105 (65.62) 1.588 0.528
N1 4 3 (1.43) 1 (0.62)
NX 114 60 (28.57) 54 (33.75)

M Classification M0 266 154 (72.99) 112 (70) 1.1272 0.597
M1 4 3 (1.42) 1 (0.62)
MX 101 54 (25.59) 47 (29.38)

Radiation therapy No 338 191 (98.45) 147 (96.71) 0.5046 0.307
Yes 8 3 (1.55) 5 (3.29)

Residual tumor R0 324 183 (88.83) 141 (89.24) 0.8406 1.000
R1 17 10 (4.85) 7 (4.43)
R2 1 1 (0.49) 0 (0)
RX 22 12 (5.83) 10 (6.33)

Vital status Deceased 130 88 (41.71) 42 (26.25) 8.8834 0.003
Living 241 123 (58.29) 118 (73.75)