Table 5.
Comparison of clinicopathological parameters between patients less than 57 years old and older patients.
| Characteristics | ≤57 | ≥57 | P value |
|---|---|---|---|
| Gender | |||
| Female | 88 (51.8%) | 68 (42.5%) | 0.05 |
| Male | 82 (48.2%) | 92 (57.5%) | |
| Tumor site | |||
| Right colon | 47 (27.6%) | 29 (18.1%) | 0.02 |
| Left colon | 123 (72.4%) | 131 (81.9%) | |
| Histologic subtype | |||
| Adenocarcinoma | 138 (81.2%) | 140 (87.5%) | 0.07 |
| Mucinous adenocarcinoma | 15 (8.8%) | 14 (8.8%) | |
| Others | 17 (10.0%) | 6 (3.8%) | |
| Histologic grade | |||
| Well | 88 (52.1%) | 85 (53.1%) | 0.05 |
| Moderate | 61 (36.1%) | 67 (41.9%) | |
| Poor | 20 (11.8%) | 8 (5.0%) | |
| Vascular invasion | |||
| Yes | 16 (9.4%) | 23 (14.4%) | 0.1 |
| No | 154 (90.6%) | 137 (85.6%) | |
| Perineural invasion | |||
| Yes | 14 (9.1%) | 13 (9.0%) | 0.5 |
| No | 140 (90.9%) | 132 (91.0%) | |
| Total lymph node | |||
| Mean (SD) | 24.5 (±10.30) | 17.9 (±9.06) | 0.000 |
| LN > 12 | 68 (90.7%) | 58 (80.6%) | 0.04 |
| LN < 12 | 7 (9.3%) | 14 (19.4%) | |
| Family history of cancer | |||
| Yes | 9 (5.3%) | 3 (1.9%) | 0.02 |
| No | 161 (94.7%) | 157 (98.1%) | |
| Tumor stage (T) | |||
| T1 | 3 (0.0%) | 1 (0.6%) | 0.4 |
| T2 | 22 (13.1%) | 30 (18.8%) | |
| T3 | 101 (60.1%) | 97 (60.6%) | |
| T4 | 42 (25.0%) | 32 (20.0%) | |
| Distant metastases (M) | |||
| M0 | 134 (79.8%) | 124 (78.5%) | 0.4 |
| M1 | 34 (20.2%) | 34 (21.5%) | |
| Disease stages | |||
| I | 13 (7.6%) | 15 (9.4%) | 0.6 |
| II | 80 (47.1%) | 81 (50.6%) | |
| III | 42 (24.7%) | 31 (19.4%) | |
| IV | 35 (20.6%) | 33 (20.6%) | |
| MSI status | |||
| MSI | 26 (15.3%) | 11 (6.9%) | 0.01 |
| MSS | 144 (84.7%) | 149 (93.1%) | |
| RAS mutation | |||
| Presence | 16 (46.8%) | 22 (57.9%) | 0.3 |
| Absence | 36 (42.1%) | 41 (53.2%) |
SD: standard deviation; LN: lymph node; MSI: microsatellite instability; MSS: microsatellite stable.