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. 2019 Dec 7;2019:6019637. doi: 10.1155/2019/6019637

Table 2.

Univariate analysis of OS in LUAD patients.

Parameters Univariate analysis
HR 95% CI (lower-upper) p value
Age
 <65 (N = 220) 1.000
 ≥65 (N = 273) 1.145 0.849-1.545 0.375
Gender
 Female (N = 273) 1.000
 Male (N = 230) 1.030 0.768-1.382 0.843
Pathological stage
 I/II (N = 392) 1.000
 III/IV (N = 103) 2.581 1.884-3.535 <0.001
Radiation therapy
 No (N = 392) 1.000
 Yes (N = 58) 2.016 1.372-2.962 <0.001
Residual tumour
 R0 (N = 336) 1.000
 R1/R2 (N = 16) 4.187 2.333-7.512 <0.001
Smoking history
 1 (N = 72) 1.000
 2/3/4/5 (N = 417) 0.888 0.588-1.341 0.571
Mutations
 No (N = 125) 1.000
 Yes (N = 91) 0.866 0.558-1.346 0.523
Targeted therapy
 No (N = 299) 1.000
 Yes (N = 149) 1.159 0.830-1.620 0.386
EIF3B expression
 Low (N = 247) 1.000
 High (N = 251) 1.563 1.156-2.111 0.004
eIF3D expression
 Low (N = 248) 1.000
 High (N = 250) 1.377 1.024-1.854 0.034
EIF3L expression
 Low (N = 245) 1.000
 High (N = 253) 0.710 0.528-0.955 0.023
EIF3M expression
 Low (N = 246) 1.000
 High (N = 252) 1.521 1.127-2.053 0.006

Indicates statistical significance (p < 0.05).