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Immunohistochemical staining for ABCB11 in FFPE liver sections of FNH, chronic hepatitis C, NASH, Alagille syndrome (NC3), PFIC (NC1), TPN-related liver disease (NC2), PCLD, and PSC. ABCB11 stained in brown; nuclei stained with hematoxylin in blue. In PSC, high expression and accumulation of ABCB11 at the bile canalicular membrane of adjacent hepatocytes were most consistent between different cholestatic liver diseases. Scale bar = 20 μm.
