Table 2.

The obtained results of the dissolution test of metformin 1000 mg film-coated tablets using different apparatus and volume of the medium.

	Phosphate buffer pH 6.8
	Case 1: metformin 1000 mg film-coated tablets basket, 100 rpm, 900 mL						Case 2: metformin 1000 mg film-coated tablets basket, 100 rpm, 1000 mL						Case 3: metformin 1000 mg film-coated tablets paddle, 75 rpm, 1000 mL
Time	5	10	15	20	30	45	5	10	15	20	30	45	5	10	15	20	30	45
Average	27.33	47.52	65.38	76.34	90.85	95.55	34.50	59.62	78.12	89.08	96.40	96.13	36.55	61.31	81.10	93.24	97.51	98.17
RSD	10.13	11.07	11.30	9.48	4.46	1.71	9.89	8.97	7.72	7.07	1.63	2.69	7.72	6.18	3.00	2.55	0.45	1.48
Min	25.11	43.02	56.90	67.33	83.79	92.37	28.45	49.83	66.42	78.44	93.31	91.14	32.78	56.85	78.19	90.29	97.07	96.39
Max	34.54	61.13	82.38	92.81	96.36	99.07	37.24	64.93	83.54	94.14	97.78	98.47	39.96	66.66	84.75	96.25	98.25	100.82