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(a and b) In the osteonecrotic groups, the key factors (PPARγ and C/EBP-α) controlling adipogenesis were significantly decreased compared with the control group. (c and d) On the other hand, the osteogenesis marker (osteocalcin) was significantly decreased in all of the osteonecrotic groups. (Data are presented as mean ± SD; t test, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, and the difference was statistically significant compared with the control group.)
