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. 2019 Nov 27;116(51):25891–25899. doi: 10.1073/pnas.1910334116

Table 2.

Donor characteristics

PID Gender Maximum pre-ART viral load,* c/mL CD4+ nadir, cells/µL Approximate years of infection before initial ART Current ART regimen Total years of ART experience Years of viral suppression on ART at sampling Plasma viral load on ART, c/mL CD4+ on ART, cells/µL
Patient 1 Male 412,033 16 Unknown TDF, FTC, RTG 13 1.0, not suppressed <50, 134 137, 153
1683 Male 134,406 452 2.0 FTC, TDF, RTV, DRV 5.7 5.4 <40 1,348
2669 Male Unknown 205 ≤22.0 ABC, 3TC, DTG 5.5 4.3 <40 681
3162 Male 171,000 147 11.0 RTV, DRV, ABC, DTG, 3TC 20 11.2 <40 558
R-09 Male 97,000 105 Unknown EFV, FTC, TDF 9.8 5.3§ ≤133 380
*

Abbott Diagnostics RealTime HIV-1 PCR Assay.

Same donor as in refs. 1 and 10; 2 time points, 6 mo apart.

ART failure due to drug resistance (Fig. 4) prior to suppression on new regimen including dolutegravir.

§

PID R-09 maintained viral suppression ≤133 copies/mL for 5.3 y and <40 copies/mL for 0.9 y prior to sample time point.