Fig. 8.

Otogelin and otogelin-like in mouse models of the 5 different genetic forms of Usher syndrome type 1. Confocal images of OHCs immunostained for either otogelin (Left) or otogelin-like (Right) (in green or white) and stained for actin (red). In Pcdh15^−/− mice, otogelin is detected both at the tips of the stereocilia and between stereocilia, and otogelin-like is detected mostly at the tips of the stereocilia. In the other 4 mutants, otogelin is located mostly at the tips of the stereocilia, whereas otogelin-like is detected both at the tips and between stereocilia. (Scale bars: 5 µm.)