Table 2.
Ex | Dose (mg/kg) | Parasitemia Level | % Suppression | Survival Days |
---|---|---|---|---|
CE | 100 | 54.8±0.081b*** | 2.56 | 7.00±0.44b*** |
200 | 54.72±0.88b*** | 4.27 | 7.80±0.58b*** | |
400 | 54.16±1.52b*** | 4.98 | 7.40±0.50b*** | |
DW | 10 mL | 56.24±2.23b*** | 0 | 5.80±0.37b*** |
CQ | 25 | 0.00±0.00a | 100 | 30.00±0.00 a*** |
CE | 500 | 24.56±1.55a*b*** | 41.38 | 8.60±0.50a*b*** |
750 | 22.86±0.55a**b*** | 45.44 | 9.00±0.70a**b*** | |
1,000 | 17.54±1.38a***b* | 58.13 | 9.40±0.24a**b*** | |
DW | 10 mL | 41.90±7.36b*** | 0 | 6.40±0.40b*** |
CQ | 25 | 0.00±0.00a*** | 100 | 30.00±0.00 |
Notes: Values are presented as Mean±SEM; n=5. a compared to the negative control, b compared to the positive control. *P<0.05, **P<0.01, ***P<0.001.
Abbreviations: Ex, Extract; DW, distilled water (negative control); CQ, Chloroquine (positive control); CE, crude extract.