Table 3.
Effects of n-Hexane, Chloroform, and Aqueous Fractions on Parasite Suppression and Survival Days
| Fr | Dose (mg/kg) | Parasitemia Level | % Suppression | Survival Days |
|---|---|---|---|---|
| AQf | 100 | 30.56±1.85b*** | 16.27 | 7.60±0.40b*** |
| DW | 10 | 36.50±4.01b*** | 0 | 6.60±0.24b*** |
| CQ | 25 | 0.00±0.00a*** | 100 | 30.00±0.00a*** |
| AQf | 200 | 33.28±3.87b*** | 20.57 | 9.40±0.60a*b*** |
| 400 | 32.12±31.38b*** | 23.34 | 9.40±0.92a*b** | |
| 600 | 23.10±1.79a*b** | 44.88 | 9.80±0.58a**b*** | |
| DW | 10 | 41.90±7.36b*** | 0 | 6.40±0.40b*** |
| CQ | 25 | 0.00±0.00a*** | 100 | 30.00a*** |
| Hf | 100 | 59.40±1.50b*** | 0 | 6.60±0.24b*** |
| 200 | 61.80±6.30b*** | 0 | 7.40±0.24b*** | |
| 400 | 68.20±5.56b*** | 0 | 6.80±0.24b*** | |
| Cf | 100 | 63.2±2.90b*** | 0 | 7.80±0.58b*** |
| 200 | 47.30.±3.49b*** | 15 | 8.20±0.20a*b*** | |
| 400 | 64.00±6.26b*** | 0 | 7.60±0.50b*** | |
| 3%T80 | 10 | 55.60±3.97b*** | 0 | 6.00±0.54b*** |
| CQ | 25 | 0 | 100 | 30.00±0.00a*** |
Notes: Values are presented as Mean±SEM; n=5. Values are significant at P<0.05, acompared to the negative control, b compared to the positive control. *P<0.05, **P<0.01, ***P<0.001.
Abbreviations: Fr, Fraction; DW, distilled water; 3%T80 (negative control), 3%Tween 80; CQ (positive control), chloroquine; AQF, aqueous fraction; CF, chloroform fraction; Hf, n-hexane fraction.