Table 4.
Activity of the Leaves of N. Congesta Extract and Aqueous Fraction on Paced Cell Volume in Suppressive Test
| Ex/Fr | Dose (mg/kg) | PCV | ||
|---|---|---|---|---|
| D0 | D4 | Change | ||
| AQf | 100 | 55.60±1.20 | 44.40±0.97 | −11.20±0.58b*** |
| DW | 10 mL | 57.20±0.86 | 43.60±1.02 | −13.60±0.70b*** |
| CQ | 25 | 57.20±0.85 | 57.70±0.85 | 0.50±0.60a*** |
| AQf | 200 | 56.20±0.80 | 51.20±2.08 | −8.83±3.80 |
| 400 | 54.40±1.77 | 50.20±1.59 | −7.65±1.68 | |
| 600 | 56.60±1.77 | 52.40±1.20 | − 7.29±1.35 | |
| CE | 500 | 57.80±3.27 | 53.20±1,59 | −6.97±5.10 |
| 750 | 55.40±0.67 | 51.60±1.43 | −6.80±2.87 | |
| 1000 | 55.00±2.30 | 52.40±1.80 | −4.43±3.03 | |
| DW | 10 mL | 52.00±1.04 | 43.40±2.15 | −16.61±3.52b** |
| CQ | 25 | 53.40±2.69 | 52.60±2.37 | −1.39±0.62a** |
Notes: Values are presented as Mean±SEM. a compared to the negative control, b compared to the positive control. Values are significant at P<0.05. **P<0.01, ***P<0.001.
Abbreviations: Ex/Fr, Extract/Fraction; CE, Crude Extract; DW, Distilled Water (negative control); CQ (positive control), Chloroquine; D0, Day before infection; D4, Fourth day after infection; AQF, aqueous fraction; PCV, Packed Cell Volume.