Table 6.

Effect of the Leaves of N. Congesta Extract and Aqueous Fraction on Body Weight and Temperature in Curative Test

Ex/Fr	Dose (mg/kg)	Body Weight (g)			Body Temperature (oC)
D3	D7	% Weight Change	D3	D7	% Temp Change
CE	500	24.65±0.75	22.15±0.65	−7.29±0.77b***	34.87±0.20	33.40±0.23	−4.38±0.23b***
	750	24.80±0.37	23.33±0.26	−6.04± 0.44b***	34.72±0.14	33.35±0.64	−3.81±0.32b***
	1,000	24.15±0.42	22.85±0.42	−5.38±0.36b***	35.02±0.47	33.82±0.12	−3.42±0.34b***
AQf	200	25.37±0.49	23.60±0.58	−6.95±0.95b***	34.77±0.15	33.40±0.14	−3.95±0.28b***
	400	25.00±0.52	22.90±0.50	−6.53±0.31b***	34.64±0.15	33.52±0.14	−2.82±0.54b***
	600	25.05±0.33	24.00±0.55	−5.12±1.23b***	34.57±0.17	33.66±0.24	−2.22±0.51b***
CQ	25	23.95±0.25	25.42±0.49	6.18±1.12a***	34.87±0.75	36.50±0.25	4.65±0.57a***
DW	10 mL	23.84±0.26	22.00±0.40	−8.13± 0.43b***	34.86±0.14	33.10±0.10	−5.14±1.10b***

Notes: Values are presented as mean±SEM; n=5. Values are significant at P<0.05. ^a compared to the negative control, ^b compared to the positive control. ***P<0.001.

Abbreviations: Ex/Fr, Extract/Fraction; DW (negative control), Distilled Water; CQ (positive control), Chloroquine; CE, Crude Extract; AQf, Aqueous fraction; D3, Day 3 (3 days after infection and before treatment); D7, Day 7 (7 days post-treatment); % weight change, percent of body weight change from D0 to D4; % temp change, percent of temperature change from D0 to D4.