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. 2019 Oct 22;5(3):139–154. doi: 10.1016/j.cdtm.2019.08.001

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Role of p53 in B-cell lymphoma pathogenesis. ATM: ataxia-telangiectasia mutated; ATR: ataxia telangiectasia and Rad3-related protein; CHK: checkpoint kinase; ARF: adenosine diphosphate-ribosylation factor; MDM2: mouse double minute 2 homolog; IRS: insulin receptor substrate; PI3K: phosphatidylinositol 3′-kinase; NF-κB: nuclear factor-κB; Stra6: stimulated by retinoic acid 6; BAK: B-cell lymphoma-2 homologous antagonist/killer; BAX: B-cell lymphoma-2-associated X protein; Puma: p53-upregulated modulator of apoptosis; SOD2: superoxide dismutase 2; Nrf2: nuclear factor erythroid 2-related factor 2; miRNA: micro RNA.