. 2019 Nov 27;17:100499. doi: 10.1016/j.conctc.2019.100499

Table 2.

Changes in hematological and anticoagulant activity parameters in amla and placebo intake groups throughout the trial duration.

Parameters	Placebo intake (mean ± sem)				Amla intake (mean ± sem)				ANCOVA (Among Groups)
Parameters	Before (W1, W2) or (W10, W11)	2 Weeks (W3, W4) or (W12, W13)	4 Weeks (W5, W6) or (W14, W15)	Post (3 Weeks) (W7,W9,W9) or (W16,W17,W18)	Before (W1, W2) or (W10, W11)	2 Weeks (W3, W4) or (W12, W13)	4 Weeks (W5, W6) or (W14, W15)	Post (3 Weeks) (W7,W9,W9) or (W16,W17,W18)	ANCOVA (Among Groups)
WBC (/μL)	5860 ± 419	5929 ± 480	5840 ± 383	5946 ± 419	5961 ± 383	5724 ± 452	6005 ± 471	6239 ± 530	2W: P = 0.52 4W: P = 0.92 Post: P = 0.67
WBC (/μL)		P = 0.86	P = 0.92	P = 0.81		P = 0.11	P = 0.87	P = 0.43	2W: P = 0.52 4W: P = 0.92 Post: P = 0.67
RBC (x10⁴/μL)	484.7 ± 13.6	486.6 ± 12.8	480.5 ± 12.0	481.5 ± 13.8	481.3 ± 13.3	478.5 ± 12.5	475.5 ± 12.1	486.1 ± 12.8	2W: P = 0.38 4W: P = 0.78 Post: P = 0.24
RBC (x10⁴/μL)		P = 0.59	P = 0.25	P = 0.35		P = 0.61	P = 0.31	P = 0.42	2W: P = 0.38 4W: P = 0.78 Post: P = 0.24
Hemoglobin (g/dL)	14.6 ± 0.42	14.2 ± 0.39	14.1 ± 0.37	14.5 ± 0.42	14.7 ± 0.41	14.5 ± 0.38	14.3 ± 0.38	14.4 ± 0.41	2W: P = 0.56 4W: P = 0.79 Post: P = 0.23
Hemoglobin (g/dL)		P = 0.05*	P = 0.015*	P = 0.80		P = 0.04*	P = 0.002*	P = 0.004*	2W: P = 0.56 4W: P = 0.79 Post: P = 0.23
Hematocrit (%)	44.5 ± 1.21	44.5 ± 1.51	44.1 ± 1.09	44.1 ± 1.29	44.1 ± 1.21	44.0 ± 1.17	43.7 ± 1.12	44.6 ± 1.20	2W: P = 0.92 4W: P = 1.0 Post: P = 0.16
Hematocrit (%)		P = 0.86	P = 0.20	P = 0.18		P = 0.84	P = 0.42	P = 0.39	2W: P = 0.92 4W: P = 1.0 Post: P = 0.16
Platelets Count (x10⁴/μL)	28.4 ± 2.46	28.5 ± 2.41	28.1 ± 2.17	29.2 ± 2.55	28.9 ± 2.64	28.1 ± 2.45	28.3 ± 2.23	28.7 ± 2.53	2W: P = 0.48 4W: P = 0.82 Post: P = 0.46
Platelets Count (x10⁴/μL)		P = 0.92	P = 0.57	P = 0.37		P = 0.18	P = 0.47	P = 0.82	2W: P = 0.48 4W: P = 0.82 Post: P = 0.46
PT (Sec)	11.6 ± 0.47	10.9 ± 0.17	11.9 ± 1.30	10.47 ± 0.12	11.6 ± 0.33	10.9 ± 0.23	10.3 ± 0.22	10.38 ± 0.29	2W: P = 0.11 4W: P = 0.01* Post: P = 0.013*
PT (Sec)		P = 0.13	P = 0.87	P = 0.07		P = 0.025*	P = 0.007*	P = 0.008*	2W: P = 0.11 4W: P = 0.01* Post: P = 0.013*
APTT (Sec)	31.7 ± 1.13	32.6 ± 1.44	35.8 ± 2.28	32.3 ± 1.71	32.4 ± 1.58	32.3 ± 1.56	33.5 ± 1.75	31.9 ± 1.56	2W: P = 0.73 4W: P = 0.60 Post: P = 0.81
APTT (Sec)		P = 0.67	P = 0.15	P = 0.81		P = 0.59	P = 0.64	P = 0.83	2W: P = 0.73 4W: P = 0.60 Post: P = 0.81
Platelet Aggregation (%)	96.7 ± 2.50	100 ± 0	100 ± 0	93.7 ± 5.04	86.5 ± 4.81	99.7 ± 0.28	94.0 ± 4.49	95.1 ± 2.51	2W: P = 0.30 4W: P = 0.20 Post: P = 0.28
Platelet Aggregation (%)		P = 0.095	P = 0.23	P = 0.33		P = 0.027*	P = 0.20	P = 0.16	2W: P = 0.30 4W: P = 0.20 Post: P = 0.28
MCV (fl)	91.7 ± 0.98	92.0 ± 0.99	91.9 ± 0.97	91.7 ± 0.90	91.9 ± 1.07	91.5 ± 0.92	91.8 ± 0.90	91.7 ± 0.98	2W: P = 0.04* 4W: P = 0.15 Post: P = 0.52
MCV (fl)		P = 0.16	P = 0.38	P = 1.0		P = 0.05*	P = 0.52	P = 0.37	2W: P = 0.04* 4W: P = 0.15 Post: P = 0.52
MCH (pg/cell)	30.4 ± 0.39	29.7 ± 0.32	29.7 ± 0.35	29.9 ± 0.27	30.3 ± 0.27	29.8 ± 0.31	29.7 ± 0.32	29.9 ± 0.36	2W: P = 0.57 4W: P = 0.48 Post: P = 0.89
MCH (pg/cell)		P ≤ 0.001*	P ≤ 0.001*	P = 0.003*		P ≤ 0.001*	P ≤ 0.001*	P = 0.017*	2W: P = 0.57 4W: P = 0.48 Post: P = 0.89
MCHC (g/dL)	33.1 ± 0.21	32.5 ± 0.12	32.4 ± 0.16	32.6 ± 0.18	33.1 ± 0.15	32.3 ± 0.20	32.3 ± 0.15	32.6 ± 0.20	2W: P = 0.08 4W: P = 0.03* Post: P = 0.28
MCHC (g/dL)		P ≤ 0.001*	P ≤ 0.001*	P = 0.005*		P ≤ 0.001*	P ≤ 0.001*	P = 0.03*	2W: P = 0.08 4W: P = 0.03* Post: P = 0.28