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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Biochimie. 2019 Nov 19;168:241–250. doi: 10.1016/j.biochi.2019.11.008

Figure 4. Cellular toxicity of lead compounds in nonmalignant androgen independent prostate-derived cell lines.

Figure 4.

A. PNT1A cells were plated in a 96-well plate at 1x104 cell/well in the presence of FBS or CSS. Cells were allowed to attach overnight and were treated with either vehicle (DMSO) or 10 μM of indicated compound. At 24 and 48 h, cellular viability was compared using the Cell Titer Glo Luminescent Cell Viability kit. B. RWPE1 cells were plated in a 96-well plate at 1x104 cells/well using the specified serum free media. Cells were allowed to attach overnight and treated with 10 μM of indicated compound. At 24 h and 48 h, cellular viability was compared as in A. (* signifies a difference between vehicle and treatment with ** p≤0.01, *** p≤0.001, **** p≤0.0001).