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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: J Invest Dermatol. 2019 Jul 19;140(1):85–93.e2. doi: 10.1016/j.jid.2019.07.679

Table 3.

Changes in TBRmax by Treatment Group During Randomized Controlled Trial Period

Ustekinumab
(n=22)
Placebo
(n=19)
Global change compared with baseline within group
 Mean difference* −0.102 (0.041)** 0.144 (0.014)**
 Mean % of change (95% CI)* −6.58% (−13.64% to 0.47%); (0.066) 12.07% (3.26% to 20.88%);(0.010)**
Global change compared with placebo (n=41)
 Difference of differences*** −0.246 (0.001)**
 Difference of % change*** −18.65% (−29.45% to −7.85%); (0.001)**

CI indicates confidence interval; and TBR, target-to-background ratio.

*

One sample test (P value).

**

Statistically significant findings.

***

Difference of differences (P value).

Results with NIH-read images (Primary Analysis).