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. 2019 Nov 12;19:84–96. doi: 10.1016/j.omtn.2019.10.034

Figure 2.

Figure 2

Overexpression of GAS5 Inhibits Cholesterol Efflux but Promotes Lipid Accumulation in THP-1 Macrophage-Derived Foam Cells

(A) Transfection efficiency of GAS5 in each group determined using qRT-PCR. (B) Effect of GAS5 on the cholesterol efflux of cells detected by liquid scintillation counter. (C) Effect of GAS5 on intracellular lipid accumulation examined using oil red O staining (×400). *p < 0.05 versus the sh-NC group; #p < 0.05 versus the pLV-EGFP-N group. All cellular experiments were repeated 3 times. Comparison among multiple groups was analyzed using one-way ANOVA.