Table 3.
Blood Lipid Levels of Each Group of ApoE−/− Mice (n = 8, mmol/L)
| Group | TC | TGs | HDL | LDL |
|---|---|---|---|---|
| pLV-EGFP-N | 18.49 ± 1.96 | 1.83 ± 0.19 | 1.45 ± 0.16 | 9.16 ± 0.98 |
| pLV-EGFP-GAS5 | 24.36 ± 2.59∗ | 2.64 ± 0.29∗ | 0.92 ± 0.09∗ | 16.76 ± 1.78∗ |
| sh-NC | 17.09 ± 1.71 | 1.68 ± 0.19 | 1.53 ± 0.16 | 7.61 ± 0.81 |
| sh-GAS5 | 15.13 ± 1.59# | 1.34 ± 0.15# | 1.74 ± 0.18# | 5.84 ± 0.59# |
| sh-ABCA1 | 23.49 ± 2.43# | 2.57 ± 0.26# | 0.96 ± 0.11# | 15.96 ± 1.67# |
| sh-GAS5 + sh-ABCA1 | 17.49 ± 1.83& | 1.76 ± 0.19& | 1.49 ± 0.15& | 7.64 ± 0.79& |
TC, total cholesterol; TGs, triglycerides; HDL, high density lipoprotein; LDL, low density lipoprotein; GAS5, growth arrest-specific transcript 5; ABCA1, ATP-binding cassette transporter A1.
∗
p < 0.05 versus the pLV-EGFP-N group
#
p < 0.05 versus the sh-NC group
&
p < 0.05 versus the sh-ABCA1 group; data analysis was performed by one-way ANOVA.