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. 2019 Dec 9;5:906–917. doi: 10.1016/j.trci.2019.09.004

Fig. 1.

Fig. 1

Heat map of estrogen-induced gene expression values of 15,517 genes in macaque neurons. The three columns represent placebo expression, estrogen expression, and estrogen + progesterone expression: genes were ranked by fold change (FC) of estrogen-induced expression versus placebo expression. The three panels correspond to the top 2000, middle 2000, and bottom 2000 genes ranked by FC of estrogen-treated versus placebo-treated. The figure shows progesterone to be antagonistic to estrogen in the top 2000, middle 2000, and bottom 2000 genes.