Fig. 1.

Basal ganglia mean diffusivity in baseline and follow up subtypes of Parkinson's disease (PD)

(a) Mean diffusivity of basal ganglia sub-regions in baseline (left) and follow up (right) PD sub-types. Diffuse-malignant subtype, particularly after 4.5 years of follow up, showed higher mean diffusivity of nucleus accumbens and globus pallidus. (b) Mean diffusivity of basal ganglia in follow up diffuse-malignant subtype was significantly higher than the mild motor-predominant subtype, (c) Sub-regions of basal ganglia in Brainnetome atlas. MD = mean diffusivity, L = left, R = right, vCa = ventral caudate, GP = globus pallidus, NAC = nucleus accumbens, vmPu = ventromedial putamen, dCa = dorsal caudate, dlPu= dorsolateral putamen, * = p-value < 0.05.