Table 2.
Comparison of electrophysiological measures of excitability in neurons isolated from wild-type naïve and sham-operated mice.
| Measure | Naïve | Sham | P value | Test |
|---|---|---|---|---|
| SA incidence (%) | 5.8 (4/69) | 2.4 (1/41) | 0.649 | Fisher |
| OA incidence (%) | 24.1 (14/58) | 17.1 (7/41) | 0.461 | Fisher |
| RMP (mV) | −56.9 ± 0.7 (69) | −56.6 ± 0.8 (41) | 0.724 | MW |
| AP voltage threshold (mV) | −33.6 ± 0.8 (67) | −35.4 ± 1.0 (41) | 0.409 | MW |
| Rheobase (pA) | 39.4 ± 3.4 (69) | 30.6 ± 3.4 (41) | 0.163 | MW |
For incidence measures each % value is accompanied by a ratio of the number of neurons with SA or OA over the number of neurons sampled. Other values are the mean ± SEM (number of cells sampled). Tests: Fisher's exact test (Fisher), non-parametric Mann Whitney U test (MW). AP, action potential; OA, ongoing activity; RMP, resting membrane potential; SA, spontaneous activity.