Table 3.
Electrophysiological measures of excitability in male and female wild-type mice in naïve/sham and SCI conditions.
| Measure | Male | Female | P value | Test | |
|---|---|---|---|---|---|
| Naïve/Sham | SA incidence (%) | 4.8 (2/42) | 4.4 (3/68) | 1.000 | Fisher |
| OA Incidence (%) | 19.4 (3/31) | 22.1 (15/68) | 0.169 | Fisher | |
| RMP (mV) | −54.5 ± 0.7 (42) | −58.2 ± 0.7 (68) | <0.001 | MW | |
| AP Voltage Threshold (mV) | −34.2 ± 1.0 (40) | −34.4 ± 0.8 (68) | 0.438 | MW | |
| Rheobase (pA) | 33.0 ± 4.1 (42) | 38.0 ± 3.0 (68) | 0.152 | MW | |
| SCI | SA incidence (%) | 48.9 (22/45) | 37.5 (18/48) | 0.300 | Fisher |
| OA Incidence (%) | 77.8 (35/45) | 75.0 (36/48) | 0.810 | Fisher | |
| RMP (mV) | −52.4 ± 1.2 (45) | −53.5 ± 1.1 (48) | 0.465 | t-test | |
| AP Voltage Threshold (mV) | −37.8 ± 1.0 (45) | −37.1 ± 0.8 (47) | 0.509 | MW | |
| Rheobase (pA) | 24.9 ± 4.3 (45) | 21.0 ± 2.1 (48) | 0.738 | MW |
For incidence measures each % value is accompanied by a ratio of the number of neurons with SA or OA over the number of neurons sampled. Other values are the mean ± SEM (number of cells sampled). Tests: Fisher's exact test (Fisher), non-parametric Mann Whitney U test (MW), parametric unpaired t test (t-test). AP, action potential; OA, ongoing activity; RMP, resting membrane potential; SA, spontaneous activity.