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. 2019 Nov 3;2019:5124026. doi: 10.1155/2019/5124026

Figure 4.

Figure 4

KFXOL reduces collagen production in vitro and in vivo. (a) qPCR analysis of TGF-β1 expression in fibroblasts. Data are presented as the mean ± SD; all comparisons were performed in triplicate; ∗P < 0.05; ∗∗P < 0.01. (b) Representative IHC staining of collagen I in lung tissues; collagen I expression is quantified in (c). (d) Representative IHC staining of collagen III in lung tissues; collagen III expression is quantified in (e). (f) Representative IHC staining of TIMP-1 in lung tissues; TIMP-1 expression is quantified in (g). Data were quantified using ImageJ software and presented as the mean ± SD; n = 8; ∗P < 0.05; ∗∗P < 0.01.