Table 5.
Effect of EASPA on serum biochemical parameters in the subacute toxicity study.
| Biochemical parameters | Unit | Control | 1.75 mg/kg | 3.5 mg/kg | 7 mg/kg | 14 mg/kg |
|---|---|---|---|---|---|---|
| ALP | U/L | 226.83 ±15.14 | 246.50 ± 9.75 | 245.17 ± 3.00 | 244.00 ± 3.96 | 260.83 ± 5.59 |
| ALT | U/L | 72.31 ± 3.26 | 68.35 ± 4.05 | 70.08 ± 10.00 | 74.90 ± 12.23 | 64.55 ± 8.07 |
| Glucose | mg/dL | 75.24 ± 10.03 | 80.9 ± 10.28 | 83.12 ± 22.28 | 74.38 ± 7.48 | 82.06 ± 5.05 |
| Cholesterol | mg/dL | 62.95 ± 3.56 | 63.51 ± 1.78 | 64.16 ± 2.13 | 55.03 ± 0.99 | 60.08 ± 0.77 |
| Urea | mmol/L | 7.03 ± 0.48 | 5.91 ± 0.16 | 6.03 ± 0.14 | 6.32 ± 0.23 | 5.95 ± 0.23 |
Values are expressed as a mean ± SEM (n = 6 and p < 0.05). (ALP: Serum alkaline phosphatase; ALT: serum alanine aminotransferase.)