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Activation of pro-LasA by human elastase. A, 500 ng of pro-LasA (M-LasA) was mixed with 50 ng of human NE, LasB, or PIV and incubated for 30 min, and LasA activity was measured. B, 100 ng of M-PIV (PIV purified from MW1) was mixed with 50 ng of NE or LasB and incubated for 30 min, and PIV activity was measured. **, p < 0.01; ***, p < 0.005; ns, no significance.
