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. 2019 Dec 20;17(4):1559325819895912. doi: 10.1177/1559325819895912

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Ki67 immunohistochemistry demonstrates that amitriptyline prevents the loss of proliferating cells in subgranular zone and hilus of the dentate gyrus after irradiation (A-D). Statistical analysis shows that the number of Ki67 cells reduced significantly in Exp-C. Pretreatment and posttreatment with amitriptyline prevents the loss of Ki67-labeled proliferating cells (E). **P < .01 versus the normal control group, #P < .05 versus the experimental control group.