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. 2019 Dec 20;17(4):1559325819895912. doi: 10.1177/1559325819895912

Figure 5.

Figure 5.

Parvalbumin (PV) immunohistochemistry shows that amitriptyline prevents the loss of PV immunopositive interneurons in the subgranular zone and the hilus of the dentate gyrus after irradiation (A-D). Statistical analysis shows significant reduction of PV cells in the experimental control group. Pretreatment and posttreatment with amitriptyline prevent the loss of PV-labeled interneurons significantly (E). **P < .01 versus the normal control group, #P < .05 versus the experimental control group.