Table 1.
General Characteristics of Cohort 1.a
Variable | No DCI | DCI | P |
---|---|---|---|
N | 132 | 91 | |
Female | 82 (62) | 61 (67) | .480 |
Age (year) | 55 ± 1.1 | 57 ± 1.5 | .289 |
Loss of consciousness at ictus | 53 (41) | 55 (61) | .003 |
ICU admission within 24 hours | 125 (95) | 85 (94) | .761 |
Admission GCS | 14 (13-15) | 13 (6-15) | .001 |
Transferred for intervention within 72 hours | 59 (45) | 29 (32) | .054 |
Aneurysm location | |||
Anterior circulation | 101 (77) | 72 (79) | .744 |
Posterior circulation | 23 (17) | 17 (19) | .860 |
No aneurysm found | 8 (6) | 2 (2) | .206 |
Hijdra cistern sum score | 16 (9-20) | 20 (14-23) | .001 |
Hijdra ventricular sum score | 2 (0-4) | 3 (0-6) | .010 |
Treatment day | 1.8 ± 0.2 | 2.0 ± 0.4 | .911 |
Aneurysm treatment mode | |||
Coiling | 85 (64) | 44 (48) | .019 |
Clipping | 31 (24) | 25 (28) | .532 |
No occlusion | 16 (12) | 22 (24) | .029 |
Day of DCI diagnosis | 8 ± 0.5 | ||
DCI diagnosis based on | |||
CT only | 34 (37) | ||
Clinical signs only | 31 (34) | ||
Both CT and clinical signs | 26 (29) | ||
Daily mean arterial pressure (mm Hg) | |||
Day 1 | 93.7 ± 1.1 | 99.3 ± 1.4 | .002 |
Day 2 | 97.2 ± 1.2 | 101.0 ± 1.8 | .072 |
Day 3 | 101.0 ± 1.3 | 104.0 ± 1.7 | .170 |
Mean hemoglobin (mmol/L) | |||
Day 1 | 7.97 ± 0.08 | 7.82 ± 0.10 | .251 |
Day 2 | 7.45 ± 0.08 | 7.15 ± 0.13 | .050 |
Day 3 | 7.35 ± 0.09 | 6.95 ± 0.10 | .009 |
Mean heart rate (beats per minute) | |||
Day 1 | 71.8 ± 1.1 | 73.8 ± 1.5 | .303 |
Day 2 | 69.7 ± 1.1 | 71.4 ± 1.7 | .389 |
Day 3 | 71.5 ± 1.2 | 72.8 ± 1.7 | .535 |
Lowest peripheral oxygen saturation (%) | |||
Day 1 | 89.8 ± 0.95 | 89.6 ± 0.98 | .875 |
Day 2 | 92.7 ± 0.52 | 91.7 ± 0.88 | .336 |
Day 3 | 91.6 ± 0.58 | 91.6 ± 0.58 | .943 |
GOS follow-up (months) | 3.5 ± 0.1 | 2.8 ± 0.2 | .008 |
GOS | <.001 | ||
Death | 11 (9) | 33 (39) | |
Persistent vegetative state | 0 | 1 (1) | |
Severe disability, dependent | 2 (2) | 16 (19) | |
Moderate disability, independent | 21 (17) | 10 (12) | |
Good recovery | 88 (72) | 25 (29) | |
6-month mortality | 11 (9) | 33 (38) | <.001 |
Abbreviations: DCI, delayed cerebral ischemia; ICU, intensive care unit; GCS, Glasgow coma score; CT, computed tomography; GOS, Glasgow outcome scale.
aData are reported as mean ± standard error, median (interquartile range), or number (percentage) where appropriate.