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. 2019 Dec 12;25:9471–9482. doi: 10.12659/MSM.920319

Figure 4.

Figure 4

TMUB1 regulates STAT1 and CCND1 in HCC. (A, B) Following TMUB1 overexpression, the western blotting indicated the expression of STAT1 was upregulated following TMUB1 upregulation, and CCND1 was downregulated. (C) The q-PCR indicated the change of expression of STAT1 and CCND1 was consistent with the western blots. (D, E) Following TMUB1 downregulation, the western blotting indicated the expression of STAT1 was downregulated, and CCND1 was upregulated. (F) Following TMUB1 downregulation, the q-PCR indicated the change of expression of STAT1 and CCND1 was consistent with the western blots. TMUB1 – transmembrane and ubiquitin-like domain-containing protein 1; STAT1 – signal transducer and activator of transcription 1; HCC – hepatocellular carcinoma; q-PCR – quantitative polymerase chain reaction.