Comparison 1. Pharmacy‐based management (pharmacist with or without wider team) versus treatment as usual.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Depression symptom level: improvement (intervention endpoint)	4	475	Risk Ratio (M‐H, Random, 95% CI)	0.95 [0.86, 1.05]
2 Depression symptom level: change from baseline mean depression score (intervention endpoint)	5	718	Std. Mean Difference (IV, Random, 95% CI)	‐0.04 [‐0.19, 0.10]
3 Acceptability of the intervention (as measured by participants not attending follow‐up)	12	2072	Risk Ratio (M‐H, Random, 95% CI)	1.09 [0.81, 1.45]
4 Non‐adherence to medication	6	911	Risk Ratio (M‐H, Random, 95% CI)	0.73 [0.61, 0.87]
4.1 Non‐adherence at endpoint	6	911	Risk Ratio (M‐H, Random, 95% CI)	0.73 [0.61, 0.87]