NCT03591224.

Trial name or title	Pharmacogenomic testing to optimize antidepressant drug therapy
Methods	Design: RCT Country: Canada
Participants
Interventions	Intervention: pharmacist optimising antidepressant therapy using the patient's personalised pharmacogenomic report to make recommendations. Comparator: pharmacist optimising antidepressant therapy based on standard of care
Outcomes	Primary outcomes: patient satisfaction using a brief, self‐administered multidimensional generic questionnaire comprising 17 items; severity if depression using PHQ‐9; generalised anxiety using GAD‐7; functional impairment in work/school, social life, and family life using Sheehan Disability Scale from v=baseline to 6 months. Secondary outcomes: number of pharmacist identified drug therapy problems; prescriber acceptance rate of pharmacist's recommendations at completion of study (about 1 year)
Starting date	2018
Contact information	John Papastergiou Pharmacy Ltd, Ontario, Canada Tel: 416‐461‐2453 ext 33 E‐mail: asdm500@shoppersdrugmart.ca    Wilson Li Tel: 416‐461‐7533 ext 33 Email: psdm994@shoppersdrugmart.ca
Notes